Makai Ishi Mephisto Anime Details and Episodes The story takes place in the city of demons, Shinjuku, and follows the life of Mephisto, the most powerful demon physician. Series info Watch free DetailsFormatMangaStatusFinishedSourceOriginalCountryJapan GenresActionHorrorMysterySci-Fi TagsShoujoUrban FantasyDemonsAlchemyAnti-HeroSwordplayMale Protagonist RecommendationsBai Yao PuxxxHOLiC CharactersSoyogi KazuyukiMephisto Pheles (Supporting)